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Two-carbon nitrogen ring bases (adenine and guanine) covalently linked to a sugar (ribose or deoxyribose) and one to three phosphate groups; can function as extracellular messengers, antimetabolites, and chain terminators that inhibit viral DNA polymerase.
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Uridine diphosphate glucuronic acid (UDP-α-D-glucuronic acid) is a nucleotide sugar cofactor used as the glucuronic acid donor in enzymatic glucuronidation and polysaccharide biosynthesis studies. Supplied as a high-purity research reagent, the product is provided in milligram pack sizes and includes supporting documentation for quality and safe handling.
High purity (98.0%) suitable for biochemical assays.
Provided with certificate of analysis and safety data sheet for verification.
Available in multiple milligram pack sizes to support small-scale experiments.
Used as a glucuronic acid donor in enzymatic and metabolic studies.
Stable when stored and handled according to provided instructions.
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Adenosine 5'-diphosphoribose (ADP ribose) is a nucleotide metabolite supplied as a research reagent for biochemical and analytical studies. It is used to investigate NAD+ metabolism, TRPM2 channel activation, and ADP-ribosylation pathways. Intended for research use only.
Nucleotide metabolite for biochemical and analytical assays.
Molecular formula C15H23N5O14P2; molecular weight 559.32.
Used in studies of NAD+ metabolism, TRPM2 activation, and ADP-ribosylation.
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GTP-14564 is a tyrosine kinase inhibitor targeting internal tandem duplication (ITD) and FLT3, which inhibits FLT3 ligand-dependent growth in Ba/F3 leukemia cells.
Targets internal tandem duplication (ITD) and FLT3.
Inhibits FLT3 ligand-dependent growth in Ba/F3 leukemia cells.
Used in cancer targeted therapy.
Functions as an inhibitor of Fms-like tyrosine kinase 3 (FLT3).
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BVDU 5 -Triphosphate ammonium is an antivirus agent with 5 -Triphosphate label targeting viral DNA polymerase BVDU 5 -Triphosphate ammonium shows excellent selectivity against varicella-zoster virus (VZV) and herpes simplex virus type 1 (HSV-1) due to a specific phosphorylation by the virus-encoded thymidine kinase
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ATP disodium salt (CAS 987-65-5) is a nucleotide derivative serving as the primary energy carrier in cellular metabolism It provides chemical energy through phosphate group transfer reactions facilitating numerous biochemical processes In addition to its metabolic functions ATP acts as a coenzyme involved in intracellular signaling and protein phosphorylation pathways Due to these biochemical roles ATP disodium salt is widely utilized in research exploring cellular metabolism signaling mechanisms and energy regulation pathways Recently ATP s function as a signaling molecule in immune responses and inflammation modulation has also gained attention
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Adenosine 5'-diphosphate disodium is a nucleoside diphosphate. It is the product of ATP dephosphorylation by ATPases. It acts as a platelet aggregation agent for hemostasis and the development and extension of arterial thrombosis.
Induces human platelet aggregation.
Increases cAMP levels in human platelets.
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GTP-14564 is a small-molecule tyrosine kinase inhibitor selective for internal tandem duplication (ITD) mutant and wild-type FLT3. It inhibits FLT3 ligand-dependent proliferation of Ba/F3 leukemia cells and is used as a research tool to study FLT3-driven signaling and leukemogenesis. Chemical formula C15H10N2O; molecular weight 234.25 g·mol⁻¹; reported purity 99.91%.
Targets ITD and wild-type FLT3.
Inhibits FLT3 ligand-dependent growth in Ba/F3 cells.
High reported purity suitable for biochemical assays.
Compact quantity suitable for screening and small-scale studies.
Documented in chemical databases and literature for FLT3 research.
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Chloroquine diphosphate is an antimalarial agent and inhibitor of TLR7 and TLR9 commonly used in biomedical research to modulate autophagic processes On the cellular level chloroquine diphosphate promotes autophagy through cell cycle arrest at the G1 phase involving increased expression of p27 and p53 and decreased levels of CDK2 and cyclin D1 Additionally chloroquine diphosphate enhances sensitivity of cancer cells toward chemotherapy and radiotherapy treatments by elevating autophagy and apoptotic responses In vitro studies demonstrated dose-dependent activity with reported IC50 values typically ranging from approximately 15 to 40 M depending on cell types This compound is widely utilized as an autophagy modulator and therapeutic adjuvant in tumor cell models
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